The Puzzle of Generalized Osteoarthritis (OA) — Is OA a Systemic Enthesopathy?

Synovial tissue volume: a treatment target in knee osteoarthritis (OA).

BACKGROUND Synovitis occurring frequently in osteoarthritis (OA) may be a targeted outcome. There are no data examining whether synovitis changes following intra-articular intervention. METHODS Persons aged 40 years and older with painful knee OA participated in an open label trial of intra-articular steroid therapy. At all time points they completed the Knee Injury and Osteoarthritis Outcome...

Symptoms, Signs and Quality of Life (QoL) in Osteoarthritis (OA)

Osteoarthritis is a syndrome with heterogeneous clinical presentations. Joint pain is the cardinal symptom accompanied by varying degrees of functional alterations like joint stiffness and instability. Clinical presentations are diversified, depending on which joint is affected, how severely it is affected, and the number of joints involved. The disease onset is usually subtle and unrecognized,...

Systemic Regulation of Soybean Nodulation by Acidic Growth Conditions1[OA]

Mechanisms inhibiting legume nodulation by low soil pH, although highly prevalent and economically significant, are poorly understood. We addressed this in soybean (Glycine max) using a combination of physiological and genetic approaches. Split-root and grafting studies using an autoregulation-of-nodulation-deficient mutant line, altered in the autoregulation-of-nodulation receptor kinase GmNAR...

Osteoarthritis (OA)-what’s new in diagnosis and management?

Making Sense of OA

representing a major shift for the official Journal of the International College of Neuropsychopharmacology (CINP). Moving the journal from a traditional subscription-based publication model to an (OA) model means anyone in the world with Internet access can read and make use of all the important findings presented in the journal, free of charge. This new publication model will also make the pa...